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v1.0.0 11 Nov. 2017 FINAL English version (v1.0)v1.0.1 12 Nov. 2017 Complete overhaul of start up Complete overhaul of soundtrack Processing of save files added Corrected the function to specify the version first when the voice prompts Complete overhaul of AI Complete overhaul of background Complete overhaul of rooms Complete overhaul of items Complete overhaul of M’s Complete overhaul of behaviour of M’s Complete overhaul of combat Corrected the price of Weapon and Magic Materials Version of Costume Report Corrected the images of the map screen Complete overhaul of Events Corrected the function to specify the version first when the voice prompts Corrected the images of the world map Corrected the text of the bottom screen Added background music Complete overhaul of Difficulty Complete overhaul of items Complete overhaul of UI Complete overhaul of MP Corrected the images of the map screen Complete overhaul of monsters Complete overhaul of combat Complete overhaul of the game
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Battle against the hordes of the Elden and form an army to clear the lands between! • Your Story Begins in a Drunken Town, Reborn By Fantasy Action RPG Showcasing endless possibilities, the game will grow with you from level to level, allowing you to fight monsters, progress the story, and evolve your character, all at your own pace. A large world that is combined seamlessly from large-scale open fields and huge dungeons. • Inhabitants of the Realm Come to Your Aid Through the Game’s Story. Collaborate with neighbors in solving the mystery of a young woman who disappeared, and enjoy an entertaining story line that grows through the game. • Complete and Clear the Dungeons to Increase Your Rank. Research new gear and level up! Dive into the dungeon and clear all the monsters that stand in your way! • Examine the Bigger Picture through the Poetic Ability System. Flush with splendor, dazzle the eyes with the magnificence of a great fantasy world. With the ability to create your own style, let your creativity flow and pull off awesome combos by yourself! ◆ THE NEW FANTASY ACTION RPG ◆ Rise, Tarnished, and be guided by grace to brandish the power of the Elden Ring and become an Elden Lord in the Lands Between. ◆ ABOUT THE WORLD • The Elden Ring ◆ THE THOUSAND FACES OF AN ELDEN LORD • EXAMINE THE BREATH-TURNING EXPLORATION ◆ THE COUNTRY YOU LOVE • LEVEL UP AND ACHIEVE YOUR GOAL ◆ THE COUNTRY THAT FATTENED YOUR MIND • CHOOSE YOUR TOOL: CANON ARMORS, EPIC SWORDS, AND SPELLS ◆ SUMMON THE WOODS AND AWAKEN THE DEEP THOUGHTS ◆ THE COUNTRY OF FABULOUS INCANTATIONS • EXPERIENCE A GLORIOUS FANTASY WORLD ◆ THE KINGDOM WHO RULES THE LAND ◆ THE NEW FANTASY ACTION RPG ◆ REVIEWS ELDEN RING game: ◆ The village where the story begins. Your dreams are awaiting your arrival. bff6bb2d33
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Now is the year for Legend of Heroes fans to begin their journey towards the legendary adventure, The Legend of Heroes: Trails in the Sky!
An Action RPG Embracing the World of Trails of Cold Steel
An action RPG set in Feudal Japan where two powerful nations continue their struggle, the Second World War and a civil war. The “Powers” of the nation reside in Alfea and Stoia, two branches of the Imperial Family. The mysterious “Guardian” saves the day when on a foreign journey, meeting various people and becoming drawn into their drama, in order to save the nation. But the revolution of the “Dragon’s Crest” is approaching. It will be necessary for you to create a support network and ally with the masses to save the nation.
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Never before has an action RPG continued so much between the first and second seasons of the original title. There are as many graphics and content as there were last year, and also new content such as the “Praise” buildings and music to enjoy. In addition, there are various element that have been added to the basic package.
Learn more about the contents of the Upcoming Release #2 Trailer and the Upcoming Release #3 Trailer via the links below.
Information may be subject to changes.
tag:blogger.com,1999:blog-9319737047421890058.post-24769373177920288972017-10-22T00:40:00.000-07:002017-10-22T00:40:00.587-07:00WORLD OF TEXTS Listen Up!
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Reactive Oxygen Species-Mediated Genomic Instability Leading to Lung Carcinogenesis in a Genetic Background of Lung Carcinogenesis. Lung cancer is the leading cause of cancer-related death worldwide. Although the majority of lung cancers are classified as non-small cell lung carcinoma (NSCLC), >70% are diagnosed at advanced stages due to lack of early diagnostic markers. Furthermore, prognosis and treatment options are unsatisfactory owing to its relatively high chemoresistance and recurrence rates. Cytotoxicity of reactive oxygen species (ROS) is the key for natural cellular defense against oxidative stress. However, increased ROS production may lead to DNA damage and genetic mutation. Thus, ROS-induced genomic instability leads to carcinogenesis and tumor progression. In this study, we investigated the molecular events leading to ROS-induced lung carcinogenesis using a genetic background of preneoplastic lung lesions. The major focus of this study was the toxicity of cigarette smoke (CS) on cellular ROS production and DNA damage in a mouse model of experimentally induced lung cancer. In detail, our data revealed that CS exposure increases ROS levels and induces DNA damage in a genetic background of preneoplastic lesions. In addition, we identified the DNA damage response pathways upregulated in a genetic background of preneoplastic lesions after CS exposure. This includes activation of the DNA damage sensor (Ataxia Telangiectasia Mutated), Rad3-related protein (ATR), Chk2, phospho-Chk2 (Thr68), checkpoint kinase 1, phospho-checkpoint kinase 1 (Ser345), and phospho-p53 (Ser15), which are involved in cell cycle arrest, checkpoint activation, and apoptosis. Our findings indicated that CS exposure increases ROS levels and induces genomic instability in the lung cell. Moreover, CS exposure-mediated genomic instability could lead to lung carcinogenesis in a genetic background of preneoplastic lung lesions.The effects of puerarin on vascular endothelial function and inflammatory response in rats with heart failure. To observe the effects of puerarin on vascular endothelial function and inflammatory response in rats with heart failure. One hundred and forty-four healthy male Sprague-Dawley (SD) rats were randomly divided into sham-operation group, heart failure group and puerarin-treated group. The rats in the sham-operation group, heart failure group and puerarin-treated group were respectively treated with the identical procedure but not subjected
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Minimum: OS: Windows 7 or later Processor: Intel Core i3 2nd Generation or better Memory: 4GB Graphics: Windows-compatible Nvidia or AMD GPU with 2GB or more memory DirectX: Version 11 or greater Storage: 35 GB available space Additional Notes: Games are tested on a 64-bit operating system. Some online features may require subscription. No refund is available. Recommended: Processor: Intel Core i5 3rd Generation or better
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